About Acne Vulgaris

Definition

Acne Vulgaris (AV) is a chronic inflammatory dermatosis disease notable for closed or open comedones (whiteheads and blackheads) and inflammatory lesions, including papules, nodules, or pustules (we also knew it as cysts).

acne
source: health.harvard.edu

Know About Papule, Nodule, and Pustule of Acne Vulgaris

⏩ Papule

A papule is a spot of unhealthy skin tissue that is less than one cm around. It has different borders, and it may arise in a kind of shapes. Papules are usually called skin lesions. It is fundamentally changing in the texture or color of your skin. Occasionally, papules gather together to form a rash.

⏩ Nodule

A nodule is a growth of unwell tissue. It can grow just under the skin. It can also accumulate in deeper skin tissues or internal organs. The thyroid gland and lymph nodes may develop nodules as well. People may mistake other conditions for nodules, such as abscesses or small cysts.

⏩ Pustule

Pustules are small bumps on the skin. It contains pus or fluid from the body. They ordinarily appear as white bumps surrounded by redness skin. These bumps seem very similar to pimples, but it can grow quite large. Pustules may grow on any part of the human body, but they most commonly form on the face, chest, and back. They may be found in groups in the same zone of the body.

Introduction

Acne is a general skin disease, particularly in adolescents and young adults. Thereabout 50 million people in the US have AV. Acne is suffered approximately 85% of teenagers, but it can occur in most age groups. Acne can insist into adulthood. The prevalence of this disease in adult women is about 12%. There is no mortality associated with AV, but there is often important physical and psychological morbidity, such as permanent acne scars, anxiety, poor self-image, and even depression. Acne cost is estimated to exceed $3 billion in one year.

Acne is a multi-variable inflammatory disease affecting the pilosebaceous follicles of the human skin. The recent understanding of this disease pathogenesis is continuously developing. Main pathogenic factors that play an important role in the expansion of acne are follicular hyperkeratinization, microbial colonization with Propionibacterium acnes, sebum secretion, and complex inflammatory process involving both innate and acquired immunity. Also, studies have suggested that neuroendocrine regulatory mechanisms, diet, and genetic and nongenetic variables all may contribute to the multifactorial process of acne pathogenesis.

👉 Also read more: Grading and Classification of Acne Vulgaris

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